full Prescribing Information and Medication Guide, including With ACTEMRA IV infusions, you may be able to treat your moderate to severe RA with or without. Full Prescribing Information ACTEMRA is indicated for the treatment of adult patients with moderately to severely active rheumatoid arthritis (RA) who have. Actemra® (tocilizumab) pre-filled syringe for subcutaneous (SC) injection. Patients Consumer Medicine Information (CMI). Healthcare Professionals.
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Infection signs, with or without a fever, include sweating or chills; shortness of breath; warm, red or painful skin or sores on your body; feeling very tired; muscle aches; blood in phlegm; diarrhea or stomach pain; cough; weight loss; burning when you urinate or urinating more often than normal Any of the following conditions that may give you a higher chance of getting infections. Most prescribijg, these are generic drugs. Most Popular Articles According to Rheumatologists.
Endogenous IL-6 is induced by inflammatory stimuli and mediates a variety of immunological responses. This information does not prescribin the place of talking with your healthcare provider about your medical condition or your treatment. Pegloticase Krystexxa Medication Guide: Interleukin-6 receptor antagonist; changes in clinical trials observed include decreased C-reactive protein level to within normal range, decreased values jnformation other pharmacodynamic parameters eg, rheumatoid factor, erythrocyte sedimentation rate, amyloid Aand increased hemoglobin value.
Contact the applicable plan provider for the most current information. The limited available data with ACTEMRA in pregnant women are prescribimg sufficient to determine whether there is a drug-associated risk for major birth defects and miscarriage.
The information contained in this biologic reference actwmra is offered solely for purposes of providing health care professionals with a quick and initial reference. These reactions can happen with any infusion or injection of ACTEMRA, even if they did not occur with an earlier infusion or injection.
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Pregnancy exposure registry that monitors pregnancy outcomes in women exposed to during pregnancy; patients and pregnant women are encouraged to register themselves by calling The majority resolved without any treatment and none necessitated drug discontinuation.
Forms and Documents Here you can download the form you need to enroll in Genentech Rheumatology Access Solutions and other important information. Here you can download the form you need to enroll in Genentech Rheumatology Access Solutions and other important information. IV Preparation Withdraw a volume of 0. Tocilizumab should not be infused concomitantly in the same intravenous line with other drugs.
Sweating or chills Shortness of breath Warm, red or painful skin or sores on your body Feel very tired Muscle aches Blood in phlegm Diarrhea or stomach pain Cough Weight loss Burning when you urinate or urinating more often than normal Any of the following conditions that may give you a higher chance of getting infections.
Dose interruptions are recommended for liver enzyme abnormalities, low neutrophil counts, and low platelet counts in patients with PJIA and SJIA at levels similar to what is outlined for adults with RA. Laboratory Parameters Laboratory monitoring is recommended due to potential consequences of treatment-related laboratory abnormalities in neutrophils, platelets, lipids, and liver function tests.
Most commonly, these are “non-preferred” brand drugs. The information contained in this section of the site is intended for U. Total infusion time is 60 minutes with an additional 15 minutes to flush 20 mL of normal saline to clear the infusion line of medication.
Tocilizumab should not be given to patients who have experienced anaphylaxis or other severe hypersensitivity and not re-challenged.
If particulates and discoloration are noted, the product should not be used. All Interactions Sort By: Tell your healthcare provider informxtion you have these or any other side effect that bothers you or does not go away: Create Your List of Plans.
This happens most often in people who prescrkbing take nonsteroidal anti-inflammatory drugs NSAIDscorticosteroids, or methotrexate. Thanks for sharing this page. Infliximab Remicade Medication Guide: Thanks for pfescribing this page.
Step Therapy Drugs that have step therapy associated with each prescription. Tocilizumab solution does not contain preservatives; therefore, unused product remain in the vials should NOT be used.
The most commonly reported serious infections included pneumonia, gastroenteritis, varicella, and otitis media. You may also call Genentech at Anaphylaxis or serious hypersensitivity reactions have occurred, including fatalities, with informaion without concomitant arthritis therapies.
Your list will be saved and can be edited at any time. You may also have changes in other laboratory tests, such as your blood cholesterol levels.
Tell actemea healthcare provider if you are planning to become pregnant, are pregnant, plan to breast-feed, or are breast-feeding. Prescribers should exercise caution in considering the use of ACTEMRA in patients with preexisting or recent-onset demyelinating disorders. Your use of third-party websites is at your own risk and subject to the terms and conditions of use for such sites.
Genentech does not recommend and does actema endorse the content on any third-party websites. Infection signs, with or without a fever, include: Click “OK” if you are a healthcare professional.
The rate of serious infections was 9. The most common ISRs were erythema, pruritus, pain, and swelling at the injection site.