Find valuable ACTEMRA® (tocilizumab) information, including an ACTEMRA® dosing calculator, RA patient brochure, ACTEMRA® prescription guide and the. Tocilizumab (Actemra) is a biologic reference guide with prescribing information, dosage, medication administration, and possible side effects. Each vial contains 80 mg of tocilizumab* in 4 ml (20 mg/ml). . Dose interruptions of tocilizumab for the following laboratory abnormalities are recommended in.
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Notify the supervising prsecribing of the reaction. If you have polyarticular juvenile idiopathic arthritis PJIA you will have blood tests done every 4 to 8 weeks during treatment. Print this section Print the entire contents of.
If a serious infection develops, interrupt actemra prescribing information until the infection is controlled. You may also call Genentech at Do not use in pregnancy.
Promptly evaluate presctibing presenting with new-onset abdominal symptoms for early identification of GI perforation. Your doctor also has to fill out a form called the SMN. Bacterial, viral and other infections due to opportunistic pathogens.
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May cause neutropenia, decreased platelets, elevated liver transaminases, and increased lipid parameters; monitor neutrophils, platelets, lipids, and liver function tests every weeks. Patients must tell their doctor if they have these or any other actemra prescribing information effect that bothers them or does not go away:.
No dosage adjustment required Moderate-to-severe: ST Step Therapy Drugs that have step therapy associated with each prescription. In patients who develop a platelet count less than 50, per mm 3treatment is not recommended. To view formulary information first create a list of plans. Your email has been sent! There was no clear relationship between decreases in neutrophils below 1 x 10 9 per L and the occurrence of serious actemra prescribing information.
Patients with invasive fungal infections may present with disseminated, rather actemra prescribing information localized, disease. Most commonly, these are “non-preferred” brand drugs.
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Create Your List of Plans. During the 1-year study, a frequency of Do not dilute vials until after successfully obtaining intravenous access. Patients must tell their doctor if they are planning to become pregnant, are pregnant, plan to breast-feed, or are breast-feeding.
Tier Description 1 This actemra prescribing information is available at the lowest co-pay. The impact of treatment with ACTEMRA on demyelinating disorders is not known, but multiple sclerosis and chronic inflammatory demyelinating polyneuropathy were reported actemra prescribing information in clinical studies. Shortness of breath or trouble breathing Swelling of lips, tongue, or face Chest pain Feeling dizzy or faint Moderate or severe abdominal pain or vomiting.
Tell your healthcare provider if you actemra prescribing information planning to become pregnant, are pregnant, plan to breast-feed, or are breast-feeding. Monoclonal antibodies are increasingly transported across placenta as pregnancy progresses, with largest amount transferred during third trimester; risks and benefits should be considered prior to administering live or live-attenuated vaccines to infants exposed to therapy in utero.
Adults with giant cell arteritis GCA. Interleukin-6 receptor antagonist; changes in clinical trials observed actemra prescribing information decreased C-reactive protein level to within normal range, decreased values in other pharmacodynamic parameters eg, rheumatoid factor, erythrocyte sedimentation rate, amyloid Aand increased hemoglobin value.
Print with Office Info. The information contained in this section of the site is intended for U. Active Hepatic disease and Hepatic impairment—use is not recommended Live vaccines — avoid use with tocilizumab. Laboratory Parameters Laboratory monitoring is recommended due to potential consequences of treatment-related laboratory abnormalities in neutrophils, platelets, lipids, and liver function actemra prescribing information. In patients who develop an ANC less than per mm 3 treatment is not recommended.
Obtain vital signs temperature, blood pressure and pulse upon arrival, after initiation of the infusion, upon discontinuing the infusion and before the patient departs the facility. Abatacept Orencia Medication Guide: The rate of serious infections was 9. Tell your healthcare provider right away if you see any of these side effects: Most commonly, these actemra prescribing information “non-preferred” brand drugs or specialty prescription products.
Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.
Patients should be closely monitored actemra prescribing information the development of signs and symptoms of infection during and after treatment with ACTEMRA, including the possible development of tuberculosis prfscribing actemra prescribing information who tested negative for latent tuberculosis infection prior to initiating therapy.
The recommended dose of tocilizumab given once every 2 weeks as an IV infusion is: No physical or biochemical compatibility studies have been actemra prescribing information to evaluate the coadministration of tocilizumab with other drugs. Monitor patients for signs and symptoms of demyelinating disorders.