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Reduction of postpartum bleeding after expulsion of placenta. Decrease rate when labor is firmly established. Type: Biotech; Groups: Approved, Vet approved; Biologic Classification: Protein Based Therapies Hormones; Protein Structure: Db Protein Chemical. Onset: Immediately IV; few minutes nasal.
Oxytocin - Side Effects, Uses, Dosage, Overdose, Pregnancy, Alcohol | RxWiki
Pharmacokinetics Absorption: Destroyed in GI tract. Rx.
Oxytocin Injection (Pitocin) is a drug used to induce labor, control bleeding after childbirth, and for to treat incomplete or inevitable abortions. Description.
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Oxytocin Injection: MedlinePlus Drug Information
Duration: 1 h IV; 20 min nasal. Adults: Initially, no more than 0. Parenteral.
Pharmacodynamics Oxytocic action: Oxytocin increases the sodium permeability of uterine myofibrils, indirectly stimulating oxytkcin contraction of uterine smooth muscle. Metabolism: Rapidly destroyed in liver and kidneys.
Response of fetal heart rate to test may be used to evaluate oxytocin. Stop infusion to prevent fetal anoxia, turn patient on her side, and notify physician if contractions are prolonged occurring at less than 2-min intervals and if monitor records contractions about 50 mm Hg or if drugs last 90 seconds or longer.
Check fundus frequently during the first few postpartum hours and several times class thereafter. Uterine response increases with the length of the pregnancy and increases further during active labor. Drug Summary. Metabolism: Metabolized rapidly in the kidneys and liver. Oxygen administration may be necessary.
oxytocin. The threshold for response is lowered when estrogen levels are high. Distribution: Distributed throughout extracellular fluid; small amount may cross placenta.
Labor Inducers DEA Class. Adults: 10 units mixed in ml D5W or normal saline solution I. In early pregnancy, a circulating enzyme, oxytocinase, can inactivate the drug. Report change in rate and rhythm immediately. Half-life is 3 to 5 minutes.
Incidence of odytocin or allergic reactions is higher when oxytocin is drug by IM or IV injection rather than by IV oxytocin diluted solution. Stop infusion when three moderate clqss contractions occur in a minute interval. Response mimics labor contractions. Elimination: Small amounts excreted class in urine. Excretion: Only small amounts are excreted in the urine as oxytocin. Distribution: Distributed throughout the extracellular fluid; small amounts may enter the fetal circulation.
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Pitocin (Oxytocin) Induction Risks and Side Effects
If patient is receiving drug by prolonged IV infusion, watch for symptoms of oxytocin intoxication drowsiness, listlessness, headache, confusion, anuria, weight gain. If local or regional caudal, spinal anesthesia is drug given to the patient receiving oxytocin, be alert to the xoytocin of hypertensive crisis sudden intense occipital headache, palpitation, marked hypertension, stiff neck, nausea, vomiting, sweating, fever, photophobia, dilated pupils, bradycardia or tachycardia, constricting chest pain.
Report class, severe headache immediately to healthcare providers.
Infuse 0. Monitor fetal heart rate oxutocin maternal BP and pulse at least q15min during infusion period; evaluate tonus of myometrium during and between contractions and record on flow chart.
Pitocin (oxytocin) dose, indications, adverse effects, interactions from allboutn9.info
Augmentation of labor. Pharmacokinetics Absorption: Administered I. PDR, LLC.